Hypothyroidism usually manifests itself gradually over a period of years with the progressive and insidious development of one or several of the following symptoms:
- Fatigue
 - Weight Gain
 - Cold Extremities and cold intolerance
 - Decreased mental sharpness (brain fog)
 - Slow speech
 - Depression or mood swings
 - Dry skin
 - Hair loss
 - Sluggish bowel function
 - Fluid retention
 - Headaches
 - Muscle pain (fibromyalgia)
 - Joint pain
 - Tiredness after a full night’s sleep
 - Tingling and/or numbness in extremities
 - Hoarseness
 - Irregular menstrual cycles
 - Miscarriages
 - Infertility
 - Recurrent yeast vaginitis
 - Allergic disorders
 - Recurrent infections
 - Decreased sweating
 
The following are physical signs of hypothyroidism:
- The three P’s: pallor, pastiness, puffiness
 - Enlarged tongue with teeth indentations
 - Loss of hair on the lateral third of the eyebrows
 - Decreased body hair
 - Thinning hair
 - Cold extremities & cold skin
 - Dry skin
 - Brittle fingernails with ridging
 - Low blood pressure
 - Slow pulse rate
 - Low basal body temperature
 - Enlarged thyroid gland
 - Elevated cholesterol and triglycerides