Alpha-lipoic acid, or ALA, is one of the most thoroughly researched and highly regarded antioxidants in the body. As a supplement, the most biologically active form of ALA is (R)-Lipoic Acid, which provides maximum antioxidant activity at lower dosage levels.
Vital to cellular energy production, lipoic acid helps to neutralize the damage caused by free radicals, which are chemical by- products occurring from oxidation as the body converts nutrients to cellular energy. Lipoic acid serves to regenerate vitamins C and E and helps maintain levels of glutathione, a vital cellular antioxidant and liver protectant. As a supplement, (R)-Lipoic Acid appears to help increase insulin sensitivity, address metabolic syndrome, support vascular integrity, especially in the eye and nervous system, and support strong immune function.
Those undergoing chemotherapy and those with diabetes or taking anti-diabetes drugs should check with your health care provider before taking lipoic acid or any other supplement. Pregnant and lactating women are also advised to check with your healthcare provider before taking any supplement.
http://www.drweil.com/drw/u/ART03051/AlphaLipoic-Acid-ALA.html
Prothera/Klaire Labs/Complementary Prescriptions, 2015 Patient Catalog