What is NAD+?

by Mila McManus MD

Nicotinamide Adenine Dinucleotide (NAD+) is the active form of a coenzyme that is an essential component of chemical reactions that occur in all of our cells. These reactions regulate nearly every bodily process. 

Be careful of other products marketing themselves as NAD.  NAD+, NADH and NR (Nicotinamide Riboside) are not the same. Although NAD+ plays a role in the same pathway as NADH and NR, there are certain NAD+ consuming reactions where only NAD+ can be utilized. In these reactions, NADH and NR are not effective. While NADH and NR are less expensive than NAD+, the positive effects are not nearly as potent as NAD+.

NAD+ is Involved in Two Major Functions:

FIRST: Energy Production. NAD+ helps to turn carbohydrates, fats, and proteins in the body into useable energy via the Citric Acid Cycle (Krebs Cycle). This important chemical reaction results in the production of ATP. ATP is the energy currency of life, powering nearly every biological activity such as muscle contraction, protein manufacturing, and cellular communication.

SECOND: Regulating the Body’s “Stress Response”. NAD+ partners with proteins involved in regulating and preserving health. This includes synthesis and repair of DNA, regulation of circadian rhythms (sleep-wake cycle), and stem cell production.

As we age, levels of NAD+ decrease in our bodies. Scientists believe that by the time we reach our 40’s, the supply of NAD+ is no longer able to meet the demand for important biological processes. Additionally, sickness and disease, as well as environmental and self-induced stressors can rapidly deplete our body of this vital nutrient.

Additionally, low levels of NAD+ may contribute to fatigue, depression, and anxiety. It hinders our body’s ability to overcome the grip of drug and alcohol addiction. Additionally, low levels of NAD+ may contribute to worsening disease states in vital organs such as the heart, liver, and brain. NAD+ depletion weakens our immune system, which affects our ability to fight infection or slow the progression of cancer.

Reasons to consider incorporating NAD+ into your regimen:

  • The aging process
  • Athletic performance
  • Anxiety, depression and PTSD
  • Drug and alcohol addiction
  • Parkinson’s disease
  • Alzheimer’s disease
  • Other forms of Dementia
  • Multiple sclerosis
  • Other neurodegenerative disorders
  • “Chemo Brain”
  • Low energy levels
  • Chronic Fatigue Syndrome
  • Sleep disturbances
  • Chronic pain syndromes
  • Migraine headaches
  • Autoimmune diseases
  • Autoinflammatory diseases
  • Chronic Traumatic Encephalopathy (CTE)

What is the Course of Treatment for NAD+?

Treatment strategies at TWIHW are tailored to your specific needs.

We currently offer treatments consisting of 4-8 hour IV infusions of NAD+. These treatment durations vary based on treatment protocol and allow for a larger amount of NAD+ to be delivered directly to the body’s tissues, allowing depleted stores to be replenished.

For those just looking for a quick “boost”, we also offer reduced dose IV infusions that take only 2 hours.

 What Can I Expect During the NAD+ Treatment?

A brief assessment will be conducted on the day of treatment. For intravenous NAD+, a small IV will be inserted. The infusion will run for approximately 4-8 hours (or 2 hours for the reduced dose treatment). Patients are able to pass the time in our relaxing environment by watching TV, reading, and listening to music. You will also have access to high-speed internet and can bring your laptop for personal use. Water, tea, and coffee are available upon request. Please plan accordingly for meals as needed if doing a longer infusion. Delivery can be made to the facility but we ask that you refrain from any fast food or pizza.

Call our office at 281-298-6742, or visit www.twihw.com

When NAD+ IV isn’t possible, consider Tru Niagen as an alternative.

By |2021-03-24T07:09:21-05:00March 24th, 2021|Articles, General|

Supplement of the Month

Tru Niagen

In a nut shell, Tru Niagen may improve mitochondrial function (and therefore energy), may repair DNA damage, may improve sleep and brain function, may aid weight loss by speeding up metabolism, and protects the body from oxidative stress.

The following is taken from Tru Niagen’s website:

NAD (or nicotinamide adenine dinucleotide) is a vital resource found in all living cells. It plays a key role in a cell’s ability to accept and donate electrons, an important aspect of energy production at the cellular level. The human body requires it for basic life functions such as sleeping, eating, and breathing. NAD declines with age and as a result of metabolic stressors, including excessive electromagnetic radiation, over-eating, or drinking alcohol. 

In 2004, Dr. Charles Brenner discovered that nicotinamide riboside (NR) could increase levels of a vital cellular resource. This resource is a central regulator in energy metabolism and is believed to play an important role in healthy human aging. Based on Dr. Brenner’s patents and the established techniques of our parent company ChromaDex, NR was exclusively licensed and developed as NIAGEN®.

One capsule of Tru Niagen Pro® contains 500mg of NIAGEN®, a patented and FDA safety-notified form of vitamin B3 known as nicotinamide riboside (NR). Tru Niagen® is formulated without nuts or gluten. It contains no caffeine, no animal byproducts, and no artificial colors or flavors.

Tru Niagen® will start increasing NAD levels shortly after you take it and will continue to maintain those elevated NAD levels with regular supplementation. It may take some time to feel the benefits of increased NAD (promoting cellular repair, increasing cellular energy, etc.), but ultimately Tru Niagen® is helping your cells remain energized and resilient in the face of everyday stresses.*

Tru Niagen® is safe when used as directed. Its sole active ingredient Niagen® has been studied in multiple published human clinical trials and no adverse events have been attributed to its use. Niagen® has twice been successfully reviewed under FDA’s new dietary ingredient (NDI) notification program and has also been successfully notified to the FDA as generally recognized as safe (GRAS).

Over 150 scientific articles have been published on our key ingredient, nicotinamide riboside, and its benefits since its discovery as an NAD booster in 2004. The number of nicotinamide riboside studies coming out each year is steadily increasing as scientists continue to uncover the potential of this remarkable nutrient.

Available at TWIHW

References:

https://www.truniagen.com/

https://www.healthline.com/nutrition/nicotinamide-riboside#bottom-line

By |2020-07-07T09:58:27-05:00July 8th, 2020|Articles, General|
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