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About Mila McManus MD

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So far Mila McManus MD has created 864 blog entries.

Could this help you?

by Mila McManus MD

If you are familiar with my practice and know that we work hard to heal and restore health in everyway possible without using prescription drugs, you may be wondering why I am excited to tell you about Low Dose Naltrexone (aka LDN).  For three reasons, I believe this is a great example of a very useful drug. LDN does not mask symptoms.  It addresses the issues of dysregulation of the immune system (and regulates it) and issues of inflammation (by reducing it).  And finally, LDN has no known side effects other than transient effect on sleep and vivid dreams.

Since inflammation and immune dysregulation are at the root of many diseases, especially autoimmunity, clinicians are using it for a whole range of conditions involving inflammation and immune dysregulation including Hashimoto’s, Grave’s, rheumatoid arthritis, lupus, psoriasis, MS, ALS, alopecia, chronic fatigue syndrome, and neurogenerative disorders such as Parkinson’s and Alzheimer’s.  LDN is also used as a complementary medicine by functional specialists for cancers, HIV/AIDS, as well as for post radiation salivary gland destruction, chronic allergic rhinitis, nerve damage, autism, shingles, weight management, infertility and migraines.

The original commercial prescription use of Naltrexone was approved by the FDA in 1984 in a 50mg dose and used for helping opiate addicts get off illegal and prescription drugs by blocking opiate receptors.  It’s also used to reverse opiate overdose (e.g., heroin, morphine).

Since that time, many doctors have pioneered the use of Naltrexone at very low doses, thus the name, Low Dose Naltrexone, or LDN.  One of the first was Bernard Bihari, MD, a physician in New York City who was interested in treating cancer and AIDS patients.  He discovered that low doses between 3 and 4.5 mg had very beneficial effects on the immune system.

Over the last 25 years or so, there have been increasingly more clinical trials with very favorable results. Additionally, clinical and anecdotal experience is showing improvements for a wide variety of conditions. So far, two main mechanisms of LDN have been identified.

First, LDN modulates the immune system by helping the T regulatory cells balance immune function without suppressing the body’s ability to regenerate and repair.  T regulatory cells are responsible for turning inflammation on and off in the body.  Patients with overactive immune systems (such as asthma, allergies, and autoimmune conditions) have immune systems that get “stuck in overdrive”.  LDN helps to get the system balanced again.

Second, LDN reduces inflammation in the Central Nervous System which is thought to play a significant role in fibromyalgia, other forms of chronic pain, and depression.  In the Central Nervous System there are receptors found on certain brain cells called microglia.  These cells can become chronically activated, resulting in neurotoxicity, which causes a cascade of symptoms that are associated with chronic pain, fatigue, mood disorders, and cognitive problems.  LDN reduces inflammation and quiets the microglia, which slows or stops the cascade of symptoms.

Another important advantage is that LDN is safe for almost everyone. People who regularly use opioid drugs or medication should not take LDN (however, there is a new FDA approved morphine that has a VERY low dose of LDN combined with it).  LDN is not addictive and can be stopped abruptly without harm or withdrawal.

While most conventional healthcare practitioners are not familiar with LDN, it’s gaining popularity in the functional medicine realm. At TWIHW, we’ve been prescribing LDN for several years for all sorts of health issues.  Because it’s specially compounded, it’s not covered by insurance.  Dosing is very personalized for each patient. In our practice, dose varies from 0.5mg per day, up to 4.5mg twice daily.  It can be formulated into capsules, sublingual drops, topical cream, nasal spray, and eye drops, depending on the purpose or need.

Studies with LDN have been especially encouraging for treating Crohn’s with over a 70% remission rate, and even complete mucosal healing as evidenced by colonoscopy in some cases.

Because naltrexone has been without patent protection for many years, no pharmaceutical company will bear the expense of the large clinical trials necessary for FDA approval of LDN’s new special uses.  There are at least 2 new FDA-approved and patented combination drugs (one mentioned above, and a new weight management drug called CONTRAVE®) which include LDN.  They always find a way!!

 

Resources:

https://www.ldnscience.org/patients/qa/how-does-low-dose-naltrexone-work

http://www.lowdosenaltrexone.org/

https://chriskresser.com/low-dose-naltrexone-ldn-as-a-treatment-for-autoimmune-disease/

https://www.ldnresearchtrust.org/what-is-ldn

By |2018-06-11T08:37:08-06:00May 5th, 2018|Articles, General|

“I am so glad I found Dr. McManus.”

I am so glad I found Dr. McManus.

After going to 5 doctors in conventional medicine I finally decided to branch out to functional medicine. I am so glad I found Dr. McManus. She treated each one of my many symptoms which ranged from anxiety, awful reflux, sleep issues, moodiness, but most of all a nerve issue. She set out a detailed plan with diet, supplements and testing. I felt so much better after the diet reset and taking the proper nutrients my body so desperately needed. Dr. McManus’ whole staff is extremely well trained to help you with anything that comes up. I loved the weekly email check-ins while on the diet cleanse. They give you the resources to help you and they really want you to feel your very best.

From Lana P.

Thanks 

By |2018-06-20T20:22:52-06:00April 16th, 2018|General, Testimonials|

Recipe of the Month: Chicken Fried Meatballs

Chicken Fried Meatballs

From Well Fed Weeknights

Ingredients:

Meatballs:

    • 1 1/2 pounds ground chicken

    • 1 teaspoon salt

    • 1/2 teaspoon ground black pepper

    • 2 tablespoons extra-virgin olive oil

Coating:

  • 3 tablespoons tapioca starch

  • 1/2 teaspoon salt

  • 1/2 teaspoon smoked paprika

  • 1/4 teaspoon ground black pepper

  • 1/4 teaspoon rubbed sage

  • 1/4 teaspoon coarse (granulated) garlic powder

  • 1/4 teaspoon coarse (granulated) onion powder

  • pinch dried marjoram

  • pinch ground cayenne pepper

  • pinch ground cloves

 

Directions:

      1. 1. Preheat the oven to 425F. Line a rimmed baking sheet with parchment paper.

      1. 2. Season the chicken. Place the ground chicken, salt, and pepper in a large mixing bowl; mix well.

      1. 3. Make the coating. In a shallow bowl, use a fork to combine the tapioca starch, salt, smoked paprika, black pepper, sage, garlic powder, onion powder, marjoram, cayenne pepper, and cloves.

      1. 4. Make the balls. Moisten your hands with cold water, then measure rounded tablespoons of ground chicken and roll the chicken into balls. Roll each ball in the seasoned tapioca starch. Set the chicken balls aside on the baking sheet until you’re ready to fry them.

      2. 5. Fry the balls. Place 1 tablespoon oil in a large, nonstick skillet over high heat, 2–3 minutes. Place half of the meatballs in a single layer in the pan, leaving some wiggle room around them. Cook until they’re browned on all sides, 4–5 minutes total. Transfer the balls to the baking sheet. Add 1–2 teaspoons oil to the pan and brown the remaining meatballs and transfer them to the baking sheet. Place the baking sheet in the oven and set a timer for 10 minutes.

By |2018-05-23T12:23:36-06:00April 16th, 2018|Articles, General, Recipes|

Supplement of the Month: Pure Paleo Protein Powder

Supplement of the Month

Pure Paleo Protein Powder

By Designs for Health

Considering recent testing, rendering so many protein powder options in the marketplace very toxic (see related article in this issue), we are pleased to carry a protein meal replacement powder in which we can have confidence in quality and purity.

According to our representative at Designs for Health, “All our raw materials and finished products are either tested by an accredited 3rd party lab or in-house to confirm specification (we don’t rely on supplier’s Certificates of  Analysis).  We use USP/AOAC or other approved published methods from scientific journals.  We test for identity, potency, heavy metals (lead, mercury, cadmium and arsenic), micros (plate count, total yeast/mold, e.coli, salmonella and s.aureus), rancidity/oxidative markers, pesticides and perform other applicable testing depending on the ingredient/formulation.”

Pure Paleo Protein is ideal for alkalizing the body, healing and supporting bone health, and getting back on track with diet when we have slipped away into acidic foods, too much caffeine and processed foods. Non-GMO and Gluten free, this protein is sourced from beef and is very hypoallergenic.  HydroBEEF™, a proprietary highly concentrated, pure bone broth protein, has both complete and collagen proteins that are naturally found in beef and allows for better absorption to support gut, joint, bone and overall health.  Some of the key nutrients included and needed for bone support as well as overall health include boron, manganese, magnesium, calcium, zinc, and selenium. It is also a good source of most of the B vitamins. This product does NOT have a beef flavor and comes in vanilla or chocolate.  Our team and patients have found this product to be smooth, very enjoyable on the palate and satisfying as a meal replacement (or supplement) shake.

By |2018-05-23T11:55:17-06:00April 16th, 2018|Articles, General|

Nutrition Nugget: Manitoba Harvest Hemp Heart Bites

Check It Out – Portable packaging, Dessert Cookie, Breakfast or Lunchbox treat…..

Every once in a while, I see some really great new products that I know our readers will want.  Here is one you need to check out:

Manitoba Harvest Hemp Heart Bites come in a larger bag or individual snack bags. I found them at HEB in the Healthy Living section next to the chia, hemp and dried berries shelf and they are also available on line at vitacost.com and thrivemarket.com. Do you remember Pecan Sandies? That is what these remind me of in texture and enjoyment but thankfully they are chock full of good nutrition. My favorite flavor is the Cinnamon and they work great with my morning tea as a breakfast. They come in chocolate and original too.  For 230 calories in the bag and 15 grams of healthy fat, 15 grams of carbohydrate, 3 of which are fiber and the modest but helpful 10 grams of protein, it makes for a well-rounded food to enjoy. They do contain sugar so those with allergies or trying to reduce sugar or lose weight, you may simply want to enjoy a smaller portion such as 2-4 of the cookie bites rather than the serving size, which is 10 pieces. That makes them great for everyone.

By |2018-04-16T09:39:00-06:00April 16th, 2018|General, NANCY’S NUTRITIONAL NUGGET|

Various Diets Explained Series: Vegan and Vegetarian

This is the final article in this series on various diets.  This article explains the Vegan and Vegetarian diets.  Because there are formalized societies for both, we will quote directly from the Vegan Society and the Vegetarian Society to provide definition and clarification of what is included, and not included, in these diets. Then we’ll conclude with some important thoughts from a nutrition perspective.

Veganism (content directly quoted from www.vegansociety.com)

The Vegan Society (www.vegansociety.com) defines veganism as “A philosophy and way of living which seeks to exclude—as far as is possible and practicable—all forms of exploitation of, and cruelty to, animals for food, clothing or any other purpose; and by extension, promotes the development and use of animal-free alternatives for the benefit of humans, animals and the environment. In dietary terms it denotes the practice of dispensing with all products derived wholly or partly from animals. A vegan diet is richly diverse and comprises all kinds of fruits, vegetables, nuts, grains, seeds, beans and pulses.

One thing all vegans have in common is a plant-based diet, avoiding all animal foods such as meat (including fish, shellfish and insects), dairy, eggs and honey – as well as products such as leather and any products tested on animals.”

 

Vegetarianism (content directly quoted from www.vegsoc.org)

The Vegetarian Society defines a vegetarian as someone who lives on a diet of grains, pulses, legumes, nuts, seeds, vegetables, fruits, fungi, algae, yeast and/or some other non-animal-based foods (e.g. salt) with, or without, dairy products, honey and/or eggs. A vegetarian does not eat foods that consist of, or have been produced with, the aid of products consisting of or created from, any part of the body of a living or dead animal. This includes meat, poultry, fish, shellfish (sea animals covered with a shell including crustaceans and mollusks), insects, by-products of slaughter (such as gelatin, isinglass and animal rennet) or any food made with processing aids created from these.

There are different degrees of vegetarianism which may be what causes confusion for many people. The four most common forms of vegetarianism are:

  • Lacto-ovo-vegetarian. Eats both dairy products and eggs. This is the most common type of vegetarian diet.
  • Lacto-vegetarian. Eats dairy products but not eggs.
  • Ovo-vegetarian. Eats eggs but not dairy products.
  • Vegan. Does not eat dairy products, eggs, or any other animal product.

Eggs: Many lacto-ovo vegetarians will only eat free-range eggs. This is because of welfare objections to the intensive farming of hens. Through its Vegetarian Society Approved trade mark, the Vegetarian Society only endorses products containing free-range eggs.

Protein: Sources in the vegetarian diet can come from a range of different sources including:

  • Pulses, such as peas, beans, lentils and – botanically speaking – peanuts, are excellent inexpensive sources of protein and also contain minerals such as iron, zinc and calcium.
  • Soya products and QuornTM, a form of ‘myco-protein’ available as mince, burgers, fillets, sausages and so on are also good sources of protein, popular and convenient to use.
  • Free range eggs and dairy products such as milk, cheese, yoghurt as well as nuts and seeds contribute to protein and also to zinc, calcium and iron intake.
  • Vegan options such as non dairy soya milk and vegan ‘cheese’ are valuable sources of protein and are often additionally fortified with calcium.

Important Thoughts:

  • As can happen with the Standard American Diet (Omnivore), it is very easy to be attracted to highly processed, man-made vegan and vegetarian convenience foods. While we have confidence that some people can be healthy eating a vegan or vegetarian diet, it cannot be done in healthy ways any better than an omnivore’s diet if it is done on fake, highly processed or sugary options. There are many vegan and vegetarian junk food options from cheese and meat imitations as well as highly processed, fast digesting, genetically modified grains, flours and grain products.  All of these can result in a highly inflammatory diet.
  • It is important to understand that the primary purpose for vegetables in anyone’s diet is to cleanse and detoxify the human body. While it is true that carbohydrates can provide some energy, too many carbohydrates result in fat storage.  It is the nutrients and plant fibers that help us cleanse and detoxify and thus the reason many people feel so good when they initiate a vegan or vegetarian diet.  However, only protein and fat can be used to replace our cells routinely and repair damage.  No carbohydrate can be used to make new cells.  Carbohydrates cannot be used to heal bones, repair injuries or conquer disease.  This is the primary reason we emphasize the importance of responsible veganism or vegetarianism because carelessly done, it can become very difficult to have young healthy skin, maintain a healthy weight and heal from disease or illness unless you have ensured adequate and quality sources of protein and fats.
  • The ideal candidate for a vegan or vegetarian diet is a person who prefers and loves a wide variety of vegetables, nuts and seeds as well as healthy fats and is accountable to themselves to be educated and wise in ensuring optimal nutrition, and when necessary, optimal supplementation. A talent and joy for cooking and food preparation is also a good candidate since there are few vegan or vegetarian eateries. Finally, a person with a healthy digestive tract who does not suffer from food sensitivities or allergies to many of the foods in a vegetarian diet such as grains, dairy, soy, eggs and nuts – some of the highest allergenic foods in America today.
  • As we wrap this series up, please note that the same remarks can be made about any diet that is made up of processed, man-made food. Sugar, genetic modification, pesticides, hormones, antibiotics, chemicals and excessive animal foods, especially those raised in confined animal feeding operations (CAFO) cannot lead anyone to good health. We all need to take care and responsibility in determining the best diet for our unique being, by listening to our body, seeking medical assistance to carefully assess food allergies and food intolerance, nutrient status, gut health, and other sources of ill-health, inflammation and congestion.  We, as human beings, will all be best served through eating a wide variety of whole, real foods.

 

 

 

 

 

By |2018-03-25T12:09:58-06:00March 25th, 2018|Articles, General|

Beet & Black Lentil Borscht

Beet & Black Lentil Borscht**

From www.mynewroots.org

 

**A note: I hope you will treat yourself to a visit to this beautiful website. The author is a vegetarian with beautiful writing skills and her photography is also beautiful.  It is healthy eye candy to view her creations and read her experiences about food and to find creative ways to eat more vegetables whether you are a plant-based eater or not. I made this recipe last weekend, and it is both wonderful and deeply nutritious, even for people who hesitate with beets. It was well worth the effort. I’ll do it again and it is worthy of company too. I hope you will try it! I made some helpful comments below in italics.  Nancy Mehlert, MS

 

Ingredients:

    • 2 tablespoons of ghee

    • 3 leeks

    • 4 cloves of garlic

    • Pinch of salt

    • 4 bay leaves

    • 4 sprigs of fresh thyme or 1 tablespoon, dried (extra for garnish if desired)

    • 4 medium beets (1 ½ lbs.)

    • 3 medium carrots

    • 2 cups shredded cabbage of your choice

    • 3 tablespoons tomato paste

    • 1 tablespoon Dijon mustard

    • 1 teaspoon dried juniper berries (about 12)

    • 1 teaspoon caraway seeds

    • 8-10 cups vegetable broth

    • 1 cup dried black lentils (green work too)

    • 2 teaspoons apple cider vinegar

    • Cracked black pepper to taste

    • Olive oil for garnish

Directions:

      1. 1. If possible, soak the lentils overnight or for up to 8 hours in pure water. Drain and rinse well. I did this, and they also sprouted which increases the ease of digestion and nutrition. I could not find black lentils and used green instead and they worked beautifully.

      1. 2. Prepare all vegetables. Wash and slice the leeks into rounds. Mince the garlic. Peel beets and grate with a food processor or julienne by hand (the beets break down too much when grated by hand.) I chose to julienne by hand and was very pleased with their texture when I finished. Slice unpeeled carrots into rounds. Shred cabbage.

      1. 3. In a large stockpot over medium heat, melt the ghee. Add leeks and salt and cook until tender, about five minutes. Add garlic, cook 2 more minutes until fragrant. Add bay leaves, thyme, juniper berries, caraway, tomato paste, and mustard, stirring to coat the leeks and garlic. Add remaining ingredients: beets, carrots, vegetable broth (start with 8 cups and add as needed), and lentils. Reserve the cabbage. Bring to a boil, reduce to simmer and cook until the lentils are tender, about 18-22 minutes. Add cabbage and vinegar, stir and let cook for another 5 minutes. I did not have the thyme and used poultry seasoning instead which has thyme in it and I did not have the caraway seeds so I left them out. The Dijon is one of the secrets to this as are the juniper berries so be sure to add those!

      1. 4. Ladle soup into bowls, garnish with fresh thyme and plenty of cracked black pepper. Drizzle with olive oil and serve. I gave a friend two quart jars and put two more in my fridge for meals this week. Holds nicely in the refrigerator for 5-6 days.

 

 

 

 

 

 

By |2018-03-25T11:57:47-06:00March 22nd, 2018|Articles, General, Recipes|

Supplement of the Month: Botanicalm PM & Cerenity

This month we are introducing two supplements by Orthomolecular Products that we carry at TWIHW.

Botanicalm PM*is formulated to induce the relaxation needed to support better sleep for those experiencing temporary sleeplessness.  The formula includes valerian root, a well-known herb used to help with sleep-related issues and to produce a state of relaxation.  Passionflower and jujube have been used historically to produce a state of relaxation and have been used in those with overstimulation and scattered thoughts.  L-theanine, an amino acid found in green tea, supports resilience to stress by increasing alpha brain wave activity.  Hops strobile extract works in synergy with these ingredients to naturally reduce stress and induce sleep.

Cerenity* is designed to address daily stress by increasing production of the neurotransmitters serotonin and gamma-aminobutyric acid (GABA) in the brain.  Neurotransmitters are the chemical messengers that regulate mood, memory, sleep cycle and daily stress.  High levels of stress, dietary deficiencies, genetic factors, medications and toxins all play a role in neurotransmitter depletion and imbalance.  The nutrients in Cerenity support healthy neurotransmitter levels for balancing the stress response.  L-theanine, an amino acid found in green tea, has been shown to quickly improve stress perception and resilience.  PharmaGABA, a patented and naturally sourced form of GABA, has been shown to promote relaxation in the central nervous system. 5-hydroxytryptophan (5-HTP) is an amino acid intermediate that is directly converted into the mood-regulating neurotransmitter serotonin.  Taurine is an amino acid that activates GABA receptors. Inositol is crucial for the release of neurotransmitters from within nerve cells.  The essential micronutrients included in Cerenity aid in the synthesis of serotonin and GABA.  The support of these neurotransmitters helps promote a relaxed mental state, positive outlook and restful sleep cycle.

 

*These statements have been provided from OrthoMolecular Products practitioner catalog. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

By |2018-03-25T11:51:36-06:00March 16th, 2018|General|

Nutrition Nugget: Julian Bakery Pegan Seed Protein Powder

Check It Out – A Stevia Free, Smooth, Clean Vegan Protein Powder…

Every once in a while, I see some really great new products that I know our readers will want. Here is one you need to check out:

Julian Bakery Pegan (Vegan + Paleo) Seed Protein Powder– Two of the biggest and most frequent complaints I get about protein powders is the overpowering bitter taste of Stevia and/or the gritty bad taste and texture of the protein. Problems solved! This protein powder mixes up silky smooth and is sweetened with Luo Han Guo (aka. Monk Fruit), which has no aftertaste, just a nice degree of sweetness to it. The Vanilla Cinnamon is a pure pumpkin seed protein. The Double Chocolate is a Sacha Inchi seed protein. Both are easily digested. Triple Chocolate, Vanilla Cinnamon Twist or Unflavored. Available online, directly from Julianbakery.com, Amazon.com or Luckyvitamin.com

Eat Well, Be Well

 

 

 

 

 

By |2018-03-25T11:45:14-06:00March 16th, 2018|General, NANCY’S NUTRITIONAL NUGGET|

“Continuing to Stay Strong”

Continuing to Stay Strong

Good Morning Dr. McManus,

I thought I would start your morning off with some good news.

T’s health is continuing to stay strong. She made it through the second little bug since the summer – again with no antibiotics or steroids needed to clear the congestion…and no secondary infections. 🙂

Additionally, she is now ranked #3 in the state in women’s pole vault and acing all her senior classes.

R has not deviated a bit from the health reset protocol and has minimum flare ups from his gout. He is down 20 lbs and not slowing down.

Thanks again to your entire team for your program, expertise and support. You and your team are very appreciated and I hope you have a wonderful week!

Liz

By |2018-05-08T14:06:12-06:00March 12th, 2018|General, Testimonials|